Identification of Novel MicroRNAs Targeting SARS-CoV-2 through the Regulation of TMPRSS2/PI3K/AKT/PTEN Alignment in Lung Cancer: An in Silico Analysis

Mukhopadhyay, DebasmitaAlSawaftah, Nour MajdiHusseini, Ghaleb2021-05-242021-05-242021Mukhopadhyay, D., AlSawaftah, N., & Husseini, G. A. (2021). Identification of Novel MicroRNAs Targeting SARS-CoV-2 through the Regulation of TMPRSS2/PI3K/AKT/PTEN Alignment in Lung Cancer: An in Silico Analysis. ACS Pharmacology & Translational Science. https://doi.org/10.1021/acsptsci.1c000402575-9108http://hdl.handle.net/11073/21487In this study, we investigated the interactions between SARS-CoV-2 and miRNAs associated with lung cancer using bioinformatic approaches. A special focus was placed on TMPRSS2 and lung cancer progression pathways involving AKT/RAS/PI3K/PTEN genes.en-USSARS-CoV-2MicroRNALung cancerIdentification of Novel MicroRNAs Targeting SARS-CoV-2 through the Regulation of TMPRSS2/PI3K/AKT/PTEN Alignment in Lung Cancer: An in Silico AnalysisPeer-Reviewed10.1021/acsptsci.1c00040