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Technique for Drug and Gene Delivery to the Cell Cytosol
Pitt, William G. Husseini, Ghaleb
Pitt, William G.
Husseini, Ghaleb
Description
Abstract
Provided herein is a composition, a method, and a system for delivering a functional molecule to the cytosol of a cell, comprising a liposome configured to be taken into a cell, including by a process selected from the group consisting of endocytosis, pinocytosis or phagocytosis, the liposome comprising a phase transforming liquid with vapor pressure capable of forming a gas at low pressure, said liquid being associated with the liposome, and the liposome further com prising at least one functional molecule selected from the group consisting of a therapeutic molecule, a detectable label, and a targeting molecule.